These effects often depend on the specific drug or drugs used, how they are taken, how much is taken, the person's health, and other factors. Short-term effects can range from changes in appetite, wakefulness, heart rate, blood pressure, and/or mood to heart attack, stroke, psychosis, overdose, and even death.Longer-term effects can include heart or lung disease, cancer, mental illness, HIV/AIDS, hepatitis, and others.
